Biosan Bio RS-24 User manual

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Contents
1. About this edition of user instructions.......................................................................3
2. Safety precautions ...................................................................................................4
3. General information..................................................................................................5
4. Getting started..........................................................................................................6
5. Operation .................................................................................................................8
6. Program setting......................................................................................................10
7. Specifications.........................................................................................................12
8. Care and maintenance...........................................................................................13
9. Warranty.................................................................................................................14
10. EU Declaration of conformity..................................................................................15
1. About this edition of user instructions
The current edition of the user manual applies to the following models and versions
of rotators:
Mini-rotator Bio RS-24 version V.1AW
Programmable rotator Multi Bio RS-24 version V.4AW
Programmable rotator Multi RS-60 version V.3AY

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2. Safety precautions
Caution! Make sure you have fully read and understood the present Manual
before using the equipment. Please pay special attention to sections
marked by this symbol.
GENERAL SAFETY
The protection provided can be ineffective if the operation of the appliance does not
comply with the manufacturer's requirements.
Save the unit from shocks and falling.
Store and transport the unit in a horizontal position (see package label) at ambient
temperatures between -20°C and +60°C and maximum relative humidity of 80%.
After transportation or storage and before connecting it to the electric circuit, keep the
unit under room temperature for 2-3 hrs.
Use only original parts and accessories, provided by manufacturer for this product.
Before using any cleaning or decontamination methods except those recommended
by the manufacturer, check with the manufacturer that the proposed method will not
damage the equipment.
Do not make modifications in design of the unit.
ELECTRICAL SAFETY
Connect only to the mains with voltage corresponding to that on the serial number
label.
Use only the external power supply provided with this product.
Ensure that the power plug is easily accessible during use.
Disconnect the unit from the mains before moving.
If liquid penetrates into the unit, disconnect it from the mains and have it checked by
a repair and maintenance technician.
Do not operate the unit in premises where condensation can form. Operating condi-
tions of the unit are defined in the Specifications section.
DURING OPERATION
Do not operate the unit in environments with aggressive or explosive chemical mix-
tures. Please contact manufacturer for possible operation of the unit in specific at-
mospheres.
Do not operate the unit if it is faulty or has been installed incorrectly.
Do not use outside laboratory rooms.
Do not place a load exceeding maximum load value mentioned in the Specifications
section of this Manual.
BIOLOGICAL SAFETY
It is the user’s responsibility to carry out appropriate decontamination if hazardous
material is spilt on or penetrates into the equipment.

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3. General information
The rotator series include three instruments: Bio RS-24, Multi Bio RS-24 and Multi
RS-60. Models provide vertical rotation, have low power consumption and can be used in
cold rooms or incubators, operating at ambient temperature range +4°C to +40°C. The rota-
tors are applicable in all areas of laboratory research, including biochemistry and clinical
diagnostics.
Bio RS-24 mini-rotator is very simple to operate and is designed as a low-cost solu-
tion for laboratories with routine tasks. Model provides orbital rotational motion (360º) of the
platform for a duration of up to 24 hours with speed of 1-30 RPM.
Multi Bio RS-24 and Multi RS-60 programmable rotators provide three movement
types: orbital rotational motion, reciprocal motion and vibro motion of the platform in different
planes. The program features allow performing mixing motions of a particular type as well
as alternating mixing motions of different types cyclically. There are options for setting:
Orbital Rotational motion. Ordinary orbital rotational motion (360º)
of the platform for a duration of 0-250 s or non-stop, with speed of 1-
100 RPM.
Reciprocal motion. Segment of reciprocal motion when the direction
orbital rotational motion of the platform from the vertical plane is
changing in turns within the limits of the set segment (turning angle
1-90º for a duration 0-250 s, or non-stop) at set speed of the Orbital
rotational motion.
Vibro motion. Segment and duration of the Vibro motion of the plat-
form run inside the borders of reciprocal motion segment. Turning
angle 0-5º, duration 1-5 s. It is available only when the reciprocal mo-
tion is on.
Pause. Duration of the Pause runs inside the borders of reciprocal
motion segment, when Vibro motion turning angle is set to 0º, and
pause duration is 1-5 s. It is available only when the reciprocal motion
is on.
Working period from 1 min to 24 hours or non-stop.
Reciprocal motion can be started in two modes, tube position
–either horizontal or vertical.
Multi Bio RS-24 and Multi RS-60 programmablerotatorsoffer user-friendly interface,
which provides options not only for changing the program during the operation, but also for
simultaneous control over different steps of mixing protocol realization. Models will undoubt-
edly provide increased methodical means to researchers working in the field of modern mo-
lecular and cell biology and the developing medical diagnostics technology. Programmable
rotators are designed for mixing biological solutions, cell suspensions, magnetic particles
conjugated with specific antibodies as well as incubation and cultivation of biological liquids
according to the operator set program.

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4. Getting started
4.1. Unpacking. Remove packing materials carefully and retain them for future shipment
or storage of the unit. Examine the unit carefully for any damage incurred during
transit. The warranty does notcover in-transit damage.Warranty coversonly the units
transported in the original package.
4.2. Complete set. Package contents:
4.2.1. Bio RS-24:
- Bio RS-24, Mini-rotator.....................................................................................1 pce.
- PRS-22 platform...............................................................................................1 pce.
- External power supply .....................................................................................1 pce.
- Operating manual, declaration of conformity ..................................................1 copy
- PRS-4/12 platform.....................................................................................on request
- PRSC-18 platform.....................................................................................on request
PRS-22 PRS-4/12 PRSC-18
4.2.2. Multi Bio RS-24:
- Multi Bio RS-24, Programmable rotator............................................................1 pce.
- PRS-26 platform...............................................................................................1 pce.
- External power supply .....................................................................................1 pce.
- Operating manual, declaration of conformity ..................................................1 copy
- PRS-5/12 platform.....................................................................................on request
- PRS-10 platform........................................................................................on request
- PRSC-22 platform.....................................................................................on request
- PRSC-10 platform.....................................................................................on request
- M-8/50 platform.........................................................................................on request
- PRS-1DP platform.....................................................................................on request
PRS-26 PRS-5/12 PRS-10 PRSC-22
PRSC-10 M-8/50 PRS-1DP

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4.2.3. Multi RS-60:
- Multi RS-60, Programmable rotator..................................................................1 pce.
- PRS-48 platform...............................................................................................1 pce.
- External power supply .....................................................................................1 pce.
- Operating manual, declaration of conformity ..................................................1 copy
- PRS-8/22 platform.....................................................................................on request
- PRS-14 platform........................................................................................on request
PRS-48 PRS-8/22 PRS-14
4.3. Setup.
- Place the unit on horizontal even working surface.
- Remove the protective film from the display.
- Plug the external power supply into the socket at the rear side of the unit.
4.4. Platform installation or replacement.
- Unscrew the two fixing screws on the platform.
- Replace the platform and install the new platform securing it with the screws.
- Fix the screw tightly.

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5. Operation
Recommendations during operation
Arrange the tubes symmetrically in relation to the rotation axis when loading.
Figure 1. Bio RS-24
5.1. Working with model Bio RS-24
5.1.1. Connect the external power supply to the mains. Move the Power switch (fig. 1/5) to
position on.
5.1.2. Place samples on the platform: microtubes - up to the end, vacutainers and tubes
with caps - half way.
5.1.3. Set the rotation speed using the Speed knob (fig. 1/6).
5.1.4. Set the operation time using the ▼ and ▲ keys (fig. 1/3).
5.1.5. Press the Start key (fig. 1/2) to start the program.
5.1.6. The platform motion begins. Operation timer on the display (fig. 1/1) starts the count-
down. Intervals less than 1 hour are displayed in minutes and seconds, intervals more
than 1 hour - in hours and minutes.
5.1.7. If the operation timer is not set and display shows 0:00, pressing the Start key causes
continuous operation of the rotator until the Stop/Reset key (fig. 1/4) is pressed.
5.1.8. If the operation timer is set, after timer expires, the platform movement stops and the
display shows the set time interval. To reset it, press the Stop/Reset key and hold
for more than 3 seconds.
5.1.9. To repeat the set program, press the Start key.
5.1.10.If necessary, the rotator can be stopped at any time during operation by pressing the
Stop/Reset key. Pressing the Start key restarts the motion and the timer.
5.1.11.After finishing the operation, move the Power switch to position off. Disconnect the
external power supply from the mains.

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Figure 2. Multi Bio RS-24 Figure 3. Multi RS-60
5.2. Working with models Multi Bio RS-24 and Multi RS-60.
5.2.1. Connect the external power supply to the mains.
5.2.2. Place samples on the platform: microtubes - up to the end, vacutainers and tubes
with caps - half way.
5.2.3. Set the appropriate program and operation time. See the Program Setting section
of this manual.
5.2.4. Press the Run Stop key (fig. 2/9 or 3/9) to start the program.
5.2.5. The platform motion begins and the corresponding indication is shown on the display:
icon ► (fig. 2/6 or 3/6), the changing time values of the current movement type in
seconds (fig. 2/1-2/3 or 3/1-3/3, lower line) and the operation timer in hours and
minutes (fig. 2/4 or 3/4).
5.2.6. If the operation timer is not set and display shows 0:00 (fig. 2/4 or 3/4), pressing the
Run Stop key causes continuous operation of the rotator until the Run Stop key is
pressed again.
5.2.7. If the operation timer is set, after timer expires, the platform movement stops, display
shows flashing indication ■ (fig. 2/6 or 3/6) and the unit sounds a signal about the
end of operation. Press the Run Stop key to stop the signal.
5.2.8. To repeat the set program, press the Run Stop key.
5.2.9. If necessary, the rotator can be stopped at any time during operation by pressing the
Run Stop key. In this case, the platform motion stops when the platform achieves
starting position. Pressing the Run Stop key restarts the program and the timer.
Note: A step motor is used in the Multi Bio RS-24 and Multi RS-60 models.
Briefly stopping the platform with hand is allowed and does not dam-
age the mechanical parts. While the platform is held, the program
does not stop. The platform motion is automatically resumed after the
platform is released.
5.2.10.After finishing the operation, disconnect the external power supply from the mains.

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6. Program setting
Caution! Current section is applicable only for models Multi Bio RS-24 and
Multi RS-60.
Note. When setting program parameters, please mind that the unit may be
unable to operate properly in reciprocal and vibration modes with
maximum load. The recommended load is indicated in Table 1 of the
Specifications section.
6.1. Press the Select key (fig. 2/8 or 3/8) to choose the parameter to change. The active
parameter is flashing.
6.2. Use the ▼ and ▲ keys (fig. 2/7 or 3/7) to set the necessary value. If the key is pressed
for more than 2 s, the numerical values change quicker.
6.3. Saving the program does not require additional operations: the microprocessor saves
the last parameter changes as the working program automatically.
6.4. The countdown timer (fig. 2/4 or 3/4) is used to control the operation time. The timer
can be set for the period from 1 min to 24 hours.
6.5. Press and hold the Select key for 4 seconds to change the reciprocal
motion mode (tube position –either vertical or horizontal).
When the tube icon (fig. 2/5 or 3/5) is in vertical position, reciprocal rotation
starts from tubes in vertical position (platform in horizontal position).
When the tube icon is in horizontal position, reciprocal rotation starts from
tubes in horizontal position (platform in vertical position).
6.6. The examples below show separate motion types and
their available combinations in cycles. The data to the
right show the possible parameter values for each type.
6.6.1. Orbital Rotation. Set the speed of Orbital rotation (1-
100 rpm), time of Orbital rotation (1-250 s) and time for
Reciprocal motion to zero (OFF).
6.6.2. Orbital + Reciprocal Rotation. Set the speed (1-100
rpm) and time (1-250 s) of Orbital rotation. Set the turn-
ing angle (1-90º) and time (1-250 s) for Reciprocal mo-
tion. Switch off the Vibro motion by setting the time of
Vibro motion to 0 (OFF).
6.6.3. Orbital + Reciprocal + Vibro. Set the speed (1-100 rpm)
and time (1-250 s) of Orbital rotation. Set the angle (1-
90º) and time (1-250 s) for Reciprocal motion. Set the
turning angle (0-5º) and time (1-5 s) for Vibro motion.
Note that if the set time of Reciprocal motion is shorter
or equal to the set time of Vibro motion, then the Reciprocal
motion will be omitted (Orbital + Vibro).
Caution! To avoid the platform drift while performing Vibro motion, do not load
the platform over the weight that is specified in the Table 1 of the
Specifications section.

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6.6.4. Orbital + Reciprocal + Pause. Set the speed (1-100
rpm) and time (1-250 s) of Orbital rotation. Set the turn-
ing angle (1-90º) and time (1-250 s) for Reciprocal mo-
tion. Set the angle of Vibro motion mode to zero. Set
the time for Vibro/pause mode (1-5 s), which is the time
of pause duration.
Note that if the set time of Reciprocal motion is shorter or equal to the set time of
Vibro/pause mode, the Reciprocal motion mode will be omitted (Orbital + Pause).
6.6.5. Reciprocal Rotation. Set the speed (1-100 rpm) for Or-
bital rotation. Set time for Orbital rotation to zero (OFF).
Set the turning angle (1-90º) and time (1-250 s) of Re-
ciprocal motion. Set the time for Vibro motion to zero
(OFF).
6.6.6. Reciprocal + Pause. Set the speed (1-100 rpm) of Or-
bital rotation. Set time of Orbital rotation to zero (OFF).
Set the angle (1-90º) and time (1-250 s) of Reciprocal
motion. Set the time for Vibromotion type (1-5 s), which
is the time of pause duration. Set the angle of Vibro type
motion to zero.
6.6.7. Reciprocal Rotation + Vibro. Set the speed (1-100
rpm) of Orbital rotation. Set the time of Orbital rotation
to zero (OFF). Set the angle (1-90º) and time (1-250 s)
of Reciprocal motion. Set the angle (0-5º) and time (1-
5 s) of Vibro type motion.
6.6.8. Hard Vibro (only for Multi RS-60). Set the speed (1-100
rpm) of Orbital rotation. Set the time of Orbital rotation
and Vibro motion to zero (OFF). Set the angle of Recip-
rocal motion to 1°. Set the starting position of the tubes
to horizontal (see 6.5).
Caution! To avoid the platform drift while performing Vibro or Hard Vibro mo-
tion, do not load the platform over the weight that is specified in the
Table 1 of the Specifications section.
When working with the unit in vibro motion modes for long period nonstop and using
the platform with rubber clamps, choose the tubes smaller than 7 cm from cap to
bottom.

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7. Specifications
The unit is designed for operation in cold rooms, incubators (except CO2incubators)
and closed laboratory rooms at ambient temperature from +4°C to +40°C in a non-condens-
ing atmosphere and maximum relative humidity 80% for temperatures up to 31°C decreasing
linearly to 50% relative humidity at 40°C.
Biosan is committed to a continuous programme of improvement and reserves the
right to alter design and specifications of the equipment without additional notice.
Bio RS-24
Multi Bio RS-24
Multi RS-60
Orbital
rotation
Speed control
range
5-30 RPM (linear
increment)
1-100 RPM (increment 1 RPM)
Time setting
range
N/A
0-250 s (increment 1 s)
Vertical rotation
360°
Reciprocal
rotation1
Tilt angle range
N/A
1-90° (increment 1°)
Time setting
range
0-250 s (increment 1 s)
Vibro/pause
mode
Tilt angle range
N/A
0-5° (increment 1°)
Time setting
range
0-5 s (increment 1 s)
Digital countdown timer
1 min - 24 h (increment 1 min), or non-stop
Maximum operation time
8 h2
7 days
Maximum load
375 g
500 g
800 g
Dimensions
325x190x155 mm
365x195x155 mm
430x230x230 mm
Input current
DC 12 V, 110 mA
DC 12 V, 660 mA
DC 24 V, 750 mA
Power consumption
1.3 W
8 W
18 W
External power supply
input AC 100-240 V, 50/60 Hz
output DC 12 V
output DC 24 V
Weight3
1.4 kg
1.7 kg
3.8 kg
Optional
platforms
Model
Tubes
Capacity
Catalogue
number
Volume, mL
Diameter, mm
PRS-4/12
Bio RS-24
50/1.5-15
20-30/10-16
4/12
BS-010117-AK
PRSC-18
15
16
18
BS-010117-EK
PRS-5/12
Multi Bio
RS-24
50/1.5-15
20-30/10-16
5/12
BS-010117-HK
PRS-10
50
20-30
10
BS-010117-IK
PRSC-22
15
16
22
BS-010117-LK
PRSC-10
50
25-30
10
BS-010117-JK
M-8/50
50
25-30
8
BS-010117-PK
PRS-1DP
Platform for microplates and racks for 0.5-1
ml tall tubes (e.g. Thermo 3741MTX,
3742MTX, 3744MTX)
BS-010149-DK
PRS-8/22
Multi RS-
60
50/1.5-15
20-30/10-16
8/22
BS-010118-AK
PRS-14
50
20-30
14
BS-010118-BK
1
Reciprocal motion uses the same set speed as Orbital motion
2
If extended operations are neccessary, see 8.4
3
Accurate within ±10 %

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Replacement
part
Model
Tubes
Capacity
Catalogue
number
Volume, mL
Diameter, mm
PRS-22
Bio RS-24
1.5-15
10-16
22
BS-010117-FK
PRS-26
Multi Bio
RS-24
1.5-15
10-16
26
BS-010117-GK
PRS-48
Multi RS-
60
1.5-15
10-16
48
BS-010118-CK
PRS platforms are equipped with universal rubber clamps for different size tube fixa-
tion.
PRSC platforms have metal clamps able to hold heavier solutions (e.g. soil, sand).
Table 1. Recommendation of maximum allowed platform load depending on motion types
Motion type
Weight
Rotation
Up to 500 g (Bio RS-24 –up to 375 g)
Reciprocal rotation
PRS platforms - up to 350 g; PRSC platforms - up to 500 g
Vibro
1-3°
Up to 500 g
4°
Up to 350 g
5°
Up to 150 g
8. Care and maintenance
8.1. If the unit requires maintenance, disconnect the unit from the mains and contact Bio-
san or your local Biosan representative.
8.2. All maintenance and repair operations must be performed only by qualified and spe-
cially trained personnel.
8.3. Standard ethanol (75%) or other cleaning agents recommended for cleaning of labor-
atory equipment can be used for cleaning and decontamination of the unit.
8.4. Extended operation of Bio RS-24. To provide reliable operation and conserve the
resource of the motor, we recommend operation up to 8 hours, followed by a stop for
1 hour. If you require extended operation, obligatory make a 1 hour stop for each 8
hours of operation (e.g. 3 hour stop after 24 hour operation).

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9. Warranty
9.1. The Manufacturer guarantees the compliance of the unit with the requirements of
Specifications, provided the Customer follows the operation, storage and transporta-
tion instructions.
9.2. The warranted service life of the unit from the date of its delivery to the Customer is
24 months. For extended warranty, see 9.5.
9.3. Warranty covers only the units transported in the original package.
9.4. If any manufacturing defects are discovered by the Customer, an unsatisfactory
equipment report shall be compiled, certified and sent to the local distributor address.
To obtain the claim form, visit section Technical support on our website at link be-
low.
9.5. Extended warranty.
For Multi Bio RS-24 & Multi RS-60, the Premiumclass models, one year of extended
warranty is available free of charge after registration, during 6 months from the date
of sale. Online registration form can be found in section Warranty registration on
our website at the link below.
For Bio RS-24, a Basic Plus class model, extended warranty is a paid service. Con-
tact your local Biosan representative or our service department through the Tech-
nical support section on our website at the link below.
9.6. Description of the classes of our products is available in the Product class descrip-
tion section on our website at the link below.
Technical support
Registration
Product class description
biosan.lv/en/support
biosan.lv/register-en
biosan.lv/classes-en
9.7. The following information will be required in the event that warranty or post-warranty
service comes necessary. Complete the table below and retain for your records.
Model
Mini-rotator Bio RS-24
Programmable rotators Multi Bio RS-24 & Multi RS-60
Serial number
Date of sale

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10. EU Declaration of conformity
Unit type Rockers, shakers, rotators, vortexes
Models MR-1, MR-12;
3D, Multi Bio 3D, PSU-10i, PSU-20i,MPS-1, PSU-2T;
Bio RS-24, Multi Bio RS-24, Multi RS-60;
V-1 plus, V-32, MSV-3500
Serial number 14 digits styled XXXXXXYYMMZZZZ, where XXXXXX is
model code, YY and MM –year and month of production,
ZZZZ –unit number.
Manufacturer SIA BIOSAN
Latvia, LV-1067, Riga, Ratsupites str. 7/2
Applicable Directives EMC Directive 2014/30/EU
LVD Directive 2014/35/EU
RoHS2 2011/65/EU
WEEE 2012/19/EU
Applicable Standards LVS EN 61326-1: 2013
Electrical equipment for measurement, control and
laboratory use. EMC requirements. General requirements.
LVS EN 61010-1: 2011
Safety requirements for electrical equipment for
measurement, control, and laboratory use. General
requirements.
LVS EN 61010-2-051: 2015
Particular requirements for laboratory equipment for mixing
and stirring.
We declare that this product conforms to the requirements of the above Directives
____________________ ____________________
Signature Signature
Svetlana Bankovska Aleksandr Shevchik
Managing director Engineer of R&D
____________________ ____________________
Date Date
Edition 1.-4.01 - March 2018

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