Integra ASSIST PLUS User manual

128957_V01_QSG_ASSIST_PLUS_EN.docx 1/4
Quick Start Guide ASSIST PLUS PipettingRobot
This quick startguide is intended to provide a quick overview of your ASSIST PLUS’s
key features and to offer basic instructions for getting started. For detailed
information, please refer to the latest operating instructions (OI) that can be found at
www.integra-biosciences.com in different languages.
Intended Use
This is a general-purpose laboratory instrument. Any use of this instrument in a medical or IVD
setting is the sole responsibility of the user. ASSIST PLUS is used to perform pipetting operations
automatically with a VIAFLO electronic multichannel or a VOYAGER pipette attached.
Safetyinformation
Regardless of the listed safety notes, all locally applicable regulations must be observed.
1) This product may only be operated in a secure, protected network with trustworthy clients.
2) The pipette may only be usedby properly trained personnel in a manner specified by INTEGRA
Biosciences.
3) Observe the hazard warnings on the device. Keep the tower moving area free of any labware
and keep hands away.
4) Do not use or charge the instrumentnear flammablematerial or in an atmospherewith danger
of explosion. Also, do not pipette highly flammableliquids suchas acetone or ether.
5) Servicing work andrepairs may only be performed by INTEGRA Biosciences or an authorized
after-sales service member.
Gettingstarted
Set up the instrument on a perfectly horizontal surfaceaccording to the IQ/OQ document
(PN 128953). Supply voltage: 100 zH36 – 74,CAV042 – .
Insert the adapter cable in the socketon the left side of the ASSIST PLUS and connect the adapter
via a 3 core cable to the electricity mains.
a. Gripper, with lever to release the pipette
b. Tower, with Pipette arm
c. Interfaces and Main switch
d. Tip rack deck, for GripTips
e. Touch panel
f. Deck, with positions for labware
g. Instrument base
h. Wastebin, for tip ejection
i. Tip sensor, for tip monitoring
j. Reflector, for tip sensor
Switch on/off:
Press the main switch.
k. Arrow keys to move the pipette back and
fore (Y-axis), right and left (X-axis) and up
and down (Z-axis)
l. Start/Pause key
m. CommunicationLED and Error LED
n. On/Standby key
Switchon the device. Press the blinking Start/Pausekey (l) to home the ASSIST PLUS.
Remove hands from ASSIST PLUS during homing and operation.
i
g
c
d
e
f
a
j
h
k
l
m
n
b

2/4 128957_V01_QSG_ASSIST_PLUS_EN.docx
Adapting the pipette holder
Adapt the pipette holder to the used INTEGRA electronic multichannel pipette:
VIAFLO 8- or 16-channel: fold both silver levers (1, 2) down
VIAFLO 12-channel: pull the lower silver lever (2) down
VOYAGER: fold both silver levers (1, 2) up
Attaching an electronicpipette
For communicationwithASSIST PLUS, the Pipette CommunicationModule mustbe installed to the
pipette. Rotate the lower housing of the pipette by 90 degrees as displayed in the picture below.
To install a pipette, the Tip ejector opening mustfacethe Pipette
holder. Hold the pipette at an angle and insert it into the pipette
holder. Then lift up until the black gripper snaps in place.
To release the pipette, lift the black gripper by pushing down the
lever.
Enabling ASSIST PLUS program and pairing
To display the ASSIST PLUS program in the main menu of the pipette, navigate to the Toolbox.
Select Preferences - Main Menu and select ASSIST PLUS (green ).
The first time a specific pipette is connected to ASSIST PLUS, both
instrumentsneed to be paired.
Scroll to the Toolbox and press OK.
From the ASSIST PLUS menu select Bluetooth Pairing.
SwitchOFF and ON the ASSIST PLUS device and wait until the
message “Pairing successful” is displayed.
Connectionbetween ASSIST PLUS and pipette
When selecting ASSIST PLUS in the Main Menu, the pipette establishes a connection with the
ASSIST PLUS. The communicationsymbol is displayed next to the battery indicator and on the
touch panel of the ASSIST PLUS the Communication LED (m) lights up in blue.
Running a program
Placeall required labware (reservoir,plates, etc.) on the deck. From the ASSIST PLUS menu select
the program category and the program you would like to run.
Insert the tip box in the correct orientation and select the first
row/column with tips. Press the Run key of the pipette.
Press the blinking Start/Pause key (l) on the ASSIST PLUS device. It
switches to solid white, the ASSIST PLUS homes and the program is
performed automatically.
Aprogram canbepaused by pressingthe Start/Pausekey (l).Either pressthe Start/Pausekey again
to continue the program or press Abort on the pipette to abort the program.
1
2

128957_V01_QSG_ASSIST_PLUS_EN.docx 3/4
Settingup pipettingprograms
You can easily create multi-stepprograms with the VIALAB software on a PCor selecta predefined
program on the pipette and adapt the parameters to your needs.
Programcategory
Description
VIALAB Programs
Contains all programs created with VIALAB software.
Serial Dilution
Aspirate a transfer volume followed by a mix.
Repeat Dispense
Dispensemultiple aliquots of the samevolume.
Variable Dispense
Dispensemultiple aliquots of different volumes.
Multi Aspirate
Aspirate multiple aliquots of different volumes.
Plate Copy
Transfer samples between plates of the samewell number.
Reformat
Reformat12, 24, 48, 96 and 384 well plates.
Custom Programs
Create multi-stepped user-defined pipetting programs.
ASSIST PLUS’ Toolbox
The Toolbox provides a variety of options, like pairing ASSIST PLUS with a pipette, device
information, tip monitoring, tip type, park position and more.
Maintenance
Always switch off the device and disconnected form the electricity supply when carrying
out maintenance work.
Clean the ASSIST PLUS housing a lint-free cloth lightly soaked with mild soapsolution in
distilled water or with a 70 % solution of isopropanol or ethanol.
To decontaminate the ASSIST PLUS, take out the Wastebin (h) to the front, remove the waste
bin frame,the magnetically attached Sensorreflector (j) and the decks.Wipe the clean
instrument surfacewith a lint-free cloth lightly soaked with a suitable disinfectant and wipe dry
directly.
Decontaminate the Sensor reflector by spraying and wiping it with 70% Ethanol and after a
short treatment time (1-2 minutes)wiping it dry.
The aluminum decks and the waste bin with framecan be autoclaved at 121 °C for 20 min.
Equipment Disposal
ASSIST PLUS mustnot be disposed of with unsorted municipal waste.
Disposeof ASSIST PLUS in accordancewith the regulations in your area governing
disposal of devices.
Manufacturer
INTEGRABiosciencesAG
CH-7205 Zizers, Switzerland
T [phone]
F [phone]
[e-mail]
www.integra-biosciences.com
INTEGRABiosciencesCorp.
Hudson, NH 03051, USA
T [phone]
F [phone]

4/4 128957_V01_QSG_ASSIST_PLUS_EN.docx
Declarationof conformity
INTEGRA Biosciences AG –7205 Zizers, Switzerland
declares on its own responsibility that the device
Description
Model
ASSIST PLUS
4505
complies with:
EU Directives andRegulations
2014/35/EU, 2014/30/EU, 2014/53/EU, 2012/19/EC, 2011/65/EC, 1907/2006, 2019/1782
GBR Regulations
S.I. 2016/1101, S.I. 2016/1091, S.I. 2017/1206, S.I. 2013/3113, S.I. 2012/3032
For detailed, signed CEdeclaration with regulations of other countries, please refer to the
operating instructions supplied with the device.