Parker ChemTec II Assembly instructions

ENGINEERING YOUR SUCCESS.
ChemTec II
Programmable Metering Pump
Installation, Operating & Maintenance Instructions

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Parker Hannifin Corporation has a continuous policy of product development and although the Company reserves the right to
change specification, it attempts to keep customers informed of any alterations. This publication is for general information only and
customers are requested to contact contact your local Parker Sales Representative for detailed information and advice on a
product’s suitability for specific applications. All products are sold subject to the company’s Standard conditions of sale.
ChemTec II™ is a registered trademark of Parker Hannifin Corporation.

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Table of Contents
Table of Contents........................................................................................................................ 3
Precautions ....................................................................................................................................4
Standards .......................................................................................................................................6
Installation & Start-Up ..................................................................................................................6
Maintenance & Cleaning ................................................................................................................6
Introduction....................................................................................................................................6
Warranty.........................................................................................................................................7
ChemTec II Maintenance................................................................................................................7
ChemTec II Specifications..............................................................................................................8
ChemTec II Software......................................................................................................................9
Installation of the USB Driver .......................................................................................................9
Installation of Documentation Software (SciDoc II) for PC........................................................10
Start-up: Volume Flow Metering into a Bioreactor ....................................................................14
Start-up: Mass Flow Metering into a Bioreactor ........................................................................19
Start-up: Diafiltration, or Maintenance of Vessel Weight..........................................................24
Start-up: Simple pH Maintenance of a “Base” reaction .............................................................28
Front Display & Back Panel Interface.........................................................................................33
Settings.........................................................................................................................................36
ChemTec II Manual Mode...........................................................................................................41
ChemTec II Metering Applications ..............................................................................................42
Bioreactor Feed Application - General Information ...................................................................42
Linear, Volumetric Bioreactor Feed............................................................................................43
Exponential Feed - Mass Flow, Example ....................................................................................44
Appendix A................................................................................................................................46
Tubing Chart.................................................................................................................................46
Tandem Pump Head Installation and Maintenance....................................................................46
Appendix B. ...............................................................................................................................48
RH Series Pump Head Installation and Maintenance ................................................................48
Appendix C. ...............................................................................................................................55
Magnetic Gear Pump Head Installation and Maintenance.........................................................55
Notes.............................................................................................................................................67

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Precautions
READ this manual BEFORE operating or servicing this equipment.
FOLLOW these instructions carefully.
SAVE this manual for future reference.
DO NOT allow untrained personnel to operate, clean, inspect, service or tamper with
this equipment.
ALWAYS DISCONNECT this equipment from the power source before cleaning or
performing maintenance.
CALL Parker Customer Service for parts, information and service.
WARNING
DISCONNECT ALL POWER TO THIS UNIT BEFORE INSTALLING, SERVICING,
CLEANING OR REMOVING THE FUSE. FAILURE TO DO SO COULD RESULT IN
BODILY HARM AND/OR PROPERTY DAMAGE.
CAUTION
OBSERVE PRECAUTIONS FOR HANDLING ELECTROSTATIC SENSITIVE
DEVICES.
WARNING
ONLY PERMIT QUALIFIED PERSONNEL TO SERVICE THIS EQUIPMENT.
EXERCISE CARE WHEN MAKING CHECKS, TEST AND ADJUSTMENTS THAT
MUST BE MADE WITH POWER ON. FAILING TO OBSERVE THESE
PRECAUTIONS CAN RESULT IN BODILY HARM.
WARNING
FOR CONTINUED PROTECTION AGAINST SHOCK HAZARD, CONNECT TO
PROPERLY GROUNDED OUTLET ONLY. DO NOT REMOVE THE GROUND
PRONG.
IF the power cord is lost or damaged, contact Customer Service to obtain a new one. Do not replace it on your
own.

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Précautions
LISEZ ce manuel AVANT de faire fonctionner ou d’entretenir cet équipement.
SUIVEZ attentivement ces instructions.
CONSERVEZ ce manuel pour future référence.
NE LAISSEZ PAS du personnel non qualifié utiliser, nettoyer, inspecter, entretenir, réparer ou
manipuler cet équipement.
DÉBRANCHEZ TOUJOURS cet équipement de la source de courant avant de nettoyer ou d’exécuter
l’entretien.
APPELEZ PARKER pour pièces détachées, renseignements et entretien.
ATTENTION
DÉBRANCHEZ TOUT COURANT DE CETTE UNITÉ AVANT DE FAIRE
L’INSTALLATION, D’EFFECTUER L’ENTRETIEN, LE NETTOYAGE OU AVANT DE
RETIRER LE FUSIBLE. NE PAS OBSERVER CES PRÉCAUTIONS RISQUERAIT
DE CAUSER DES BLESSURES CORPORELLES OU/ET D’ENDOMMAGER
L’ÉQUIPEMENT.
PRUDENCE
SOYEZ PRUDENT LORSQUE VOUS MANIPULEZ DES APPAREILS SENSIBLES
À L’ÉLECTROSTATIQUE.
ATTENTION
AUTORISEZ SEULEMENT LE PERSONNEL QUALIFIÉ À ENTRETENIR CET
ÉQUIPEMENT. SOYEZ PRUDENT LROSQUE DES VÉRIFICATIONS, TESTS ET
AJUSTEMENTS DOIVENT ÊTRE EFFECTUÉS SOUS TENSIONS. NE PAS
OBSERVER CES PRÉCAUTIONS RISQUERAIT DE CAUSER DES BLESSURES
CORPORELLES.
ATTENTION
POUR ASSURER UNE PROTECTION CONTINUE CONTRE UNE DÉCHARGE
ÉLECTRIQUE, BRANCHEZ UNIQUEMENT SUR UNE PRISE CORRECTEMENT
RELIÉE Á LA TERRE. NE RETIREZ PAS LA FICHE DE TERRE.
SI le cordon d'alimentation est perdu ou endommagé, contactez le service clientèle pour en obtenir
un nouveau. Ne le remplacez pas par vous-même.

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Standards
EN 61326-1:2006, Class B
EN 6100-3-2:2006
EN 6100-3-3:1995 +A1:2001 +A2:2006
EN 61010-1 Issued: 2001/03/01
Conforms to UL STD 61010-1:2012 Ed.3+R:29Apr2016
Certified to: CAN/CSA-C22.2 No 61010-1-12:2012 Ed.3+U1:U2
Installation & Start-Up
Installation of the ChemTec II must be carried out only by trained personnel in accordance with the relevant
regulations and this operations manual.
Make sure that the technical specifications and input ratings of the ChemTec II are observed. See “ChemTec II
Specifications”.
The protection provided by this equipment may be impaired if the ChemTec II is used in a manner
inconsistent with this manual or for purposes not specified by the manufacturer.
Maintenance & Cleaning
The ChemTec II is practically maintenance free. The Tandem peristaltic pump head should periodically have
tubing debris cleaned from it, but requires no lubrication.
To remove dust, dirt and stains, the outer surfaces of the ChemTec II may be wiped down using a soft, non-
fluffing cloth moistened with water. If required, you may also use a mild detergent or Isopropanol.
The SciPres II disposable sensors used with the system come pre-calibrated from the factory and require no
maintenance. The SciPres II disposable sensors may be sanitized with 0.1 Molar NaOH, or Isopropanol. They
may be autoclaved once.
Introduction
You will find the ChemTec II easy to setup and use for your metering and pH control needs. The state-of-the-
art hardware and software design of the ChemTec II allows you to control measure and document your
metering processes. With proper maintenance, the ChemTec II will provide many years of excellent service
and performance.
Please read the following instructions carefully!
Inspections: Remove the products carefully from the shipping container. Check the contents against the
purchase order to verify that all parts are included and undamaged.
Please do the inspection upon receipt of the product, even if you don’t intend to use it immediately. Many
carriers must receive damage claims within 7 days of delivery. Please retain all packing material so unit may
be shipped safely, if necessary.

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If assistance is required, please contact us at:
Parker Hannifin Corporation Parker Hannifin Manufacturing Ltd
Bioscience Filtration Bioscience Filtration
2340 Eastman Avenue Durham Road
Oxnard, California, USA 93030 Birtley, Co. Durham
toll free: 877 784 2234 DH3 2SF, England
phone: [phone] phone [phone]
fax: [phone] fax [phone]
email: [e-mail] email: [e-mail]
www.parker.com/bioprocessing www.parker.com/bioprocessing
Parker customer service will be able to serve you more efficiently if you have the following information:
•Serial number and model name of the equipment
•Installation procedure being used
•Concise list of symptoms
•List of operating procedures and conditions in use when problem arose
Warranty
Country specific information can be found at: www.parker.com/termsandconditions.
ChemTec II Maintenance
Factory based preventative maintenance is recommended on an annual basis.
Contact your local Parker Sales Representative or Parker Technical Support (biosci[email protected])
to obtain a quote for this process or go to http://solutions.parker.com/service and fill out the online form.

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ChemTec II Specifications
MECHANICAL
•Dimensions: Width: 9.5 in. (24.1cm); Height: 11.5 in. (29.2cm); Depth: 13.4 in. (34cm)
•Weight: 16.2 lbs. (7.34kg)
•Enclosure: Aluminum / Steel; Corrosion Resistant
•Accommodates a range of motor / pump heads combinations, including:
− Peristaltic pump heads, TANDEM model 1081 and 1082, either with 8, 160,
or 600 RPM motors.
− Piston pump heads, FMI model RH1, RH0 or RH00, either with 160, 600 or 3400 RPM motors.
− Magnetic gear pump heads, Micropump models 040, 120, 184, 187, 200 &
201, with 3400 RPM motors.
• Pressure Sensors: Accommodates three SciPres II Disposable pressure sensors using the P1, P2 and P3
ports. Pressure is used for monitoring and alarms. Pressure Displayed with a resolution of 0.1 psi; choice
of psi, bar, kpa.
•Pressure Range: The default pressure range of the sensors is 0-60psi. Most peristaltic pumps generate
pressures up to 30 psi. If you have need for higher pressures, contact Parker Technical Support
([email protected]) for assistance.
ELECTRICAL
•Power: 100-240 V , 50/60 Hz, 150 VA, Class 2 switching power supply; fuse: 3.15A-T20, 250V
•Battery: CR1632, used to support the internal clock only, not user serviceable.
•Motor: Choice of four motors: 8, 160, 600 and 3400 RPM at 24V , 3.8 Amperes, Variable Pump Speed
optically encoded, servo-controlled motors.
•Encoder: 100 lines/rev. for 600-RPM motor. 120 lines per/rev. for all other motors.
•I/O Ports:
− “Printer”, Female DB9 connector for data collection with Printer or PC.
− “S1”, “S2”, “S3”, Male DB9 connectors for RS-232 connection to an electronic scale.
− “P1, P2, P3”, Amphenol connectors for SciPres II disposable Pressure Sensors.
− “ANALOG”, Female DB25 for up to 8 Analog (4-20 mA) inputs and 4 Analog outputs.
− “DIGITAL”, Female DB25 for 8 TTL Digital Outputs and 8 TTL Digital Inputs.
− “PROFIBUS” Female DB9 for Profibus communication. Disabled
− “CAN IN” Male DB9 for CAN communication input. Disabled
− “CAN OUT” Male DB9 for CAN communication output. Disabled
− “USB1, USB2, USB3”, USB connectors, used for storage and retrieval of recipes.
− “Ethernet”, RJ-45 connector. Disabled
− “RELAY1”, “RELAY2” Six 250 V, 8A NO relays, three on each connector.
ENVIRONMENTAL
• Temperature range: 4 to 40°C.
• Altitude: up to 2000 Meters
• Indoor, dry environments only, clean-up is wipe down only. (IP 20)
• Relative humidity: 0-95%
• Voltage fluctuations +/- 10%
• Pollution degree: 2

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ChemTec II Software
The ChemTec II is recipe driven. You can create recipes for the following processes:
•Volume Flow: Programmable volumetric metering.
•Mass Flow: Programmable gravimetric metering, which requires an electronic balance.
•Diafiltration: Maintains weight of monitored vessel and requires an electronic balance. Can be additive or
subtractive.
•pH Control: Provides control of pH Maintenance and/or End Point Titration via connection to pH meter with
4-20 ma output.
The ChemTec II can be controlled also in Manual Mode by % of motor speed. Pump settings and Alarms can be
configured by the end user.
Installation of the USB Driver
Upon connecting the ChemTec II to the PC via the provided RS232 to USB adapter cable on the Printer Port of
the ChemTec II, open Control Panel, then Device Manager on your PC.
The listing for the cable will have a yellow triangle on it indicating that the driver was not properly loaded. You
must have Administrative rights to your computer to fix this, as one must double-click on that listing and then
choose “Update Driver”. Allow the computer to search the internet for the driver and it will successfully find
and install it.
Once this is done, disconnect the cable from the computer and reinstall it. This will refresh Device Manager,
and it will now be listed as a “USB Serial Port” with an assigned COM Port.
If you provide your own adapter, follow its instructions for installation.

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Installation of Documentation Software (SciDoc II) for PC
ChemTec II’s SciDoc II Software Package provides complete process analysis with graphing of data, and real-
time verification and documentation of process parameters.
SciDoc II Software Installation
• Scan the QR code on the unit, or go to https://discover.parker.com/pump-support-gen2 and download
the SciDoc II file
• Run Setup.exe from the SciDoc II folder to automatically install
• Plug in your ChemTec II to power and connect it to your PC via an RS232 to USB adapter cable (PN 080-
USB). This will automatically create a USB Serial Port with an assigned COM Port on Windows 10 once
the drivers are downloaded off the Internet. Be sure your computer is connected to the internet with
administrative rights to open the device manager and update the cable driver if needed.
• Go to Start – All programs
• Click on SciDoc II from the SciDoc II folder to launch the welcome screen, and
select ChemTec II
• On the next screen, choose the detected / assigned serial COM Port
• Set the sec / Sample time to match the Print Time setting on the ChemTec II
• ChemTec II will automatically start sending data to SciDoc II when any mode is
executed and ran

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SAMPLE SciDoc II Screens

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SAMPLE SciDoc II Exports

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The button saves .jpg images of the charts at that time.
The button exports the data and charts as both an .xls file and a .txt file.
Files are saved at C:\Serial Data Loggers by type. All files can be readily turned into PDFs.
NOTE: The charts do not adjust their range automatically. You must manually adjust the low and high limits to
assure you have visibility of the entire data range!

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Start-up: Volume Flow Metering into a Bioreactor
EQUIPMENT
The following items are needed to get started:
Parker P/N Description Quantity
CHEM2-21 ChemTec II, CP-120 w/ 1081 Tandem Peristaltic Head, 160rpm Motor 1 pc
400-116 Silicone Tubing, Platinum Cured, #16 25 ft (1 pkg)
080-USB RS232 to USB Cable 1 pc
SciDoc II Data Collection Software Included
N/A Appropriate Media Reservoir 1 pc
N/A Appropriate Bioreactor or Fermentor 1 pc
Hardware Setup
1. Unpack all the components, visually identify and inspect for damage.
2. At the bench, place the Media reservoir to the far left. To the right of the bench, position ChemTec II, and
then the Bioreactor or Fermentor. Leave space between these items to allow for cables and tubing.
3. Connect the RS232 to USB cable between the PC and the “Printer” connector on the rear of the ChemTec
II. This cable may need a driver installed from the internet, contact your IT person if help is needed.
4. Plug in and power-up all the equipment.
5. Install SciDoc II software from https://discover.parker.com/pump-support-gen2. Choose the ChemTec II
from the menu, select the appropriate COM Port, and it will be ready to receive data from the pump.
6. If the ChemTec II and scale were purchased together from Parker, both will be configured to
communicate with each other. If purchased separately, contact Parker Technical Support
([email protected]) for assistance.
7. Cut an appropriate length of the #16 tubing and connect it to the Media reservoir. Route the tubing from
the reservoir to the ChemTec II, open the head by rotating the lever 180 degrees counter-clockwise, and
place the tubing over the upper set of rollers. Confirm that the tubing is under the centering springs and
close the head by rotating the lever back to its original position. Connect the remaining end to the
Bioreactor.
This completes the hardware and tubing configuration.
PROGRAM EDITING AND EXECUTION
At this point, please consider the parameters of the reaction being fed and determine the type of metering
needed. This can be done at a constant rate, a linear rate, or an exponential rate by using several short linear
ramps. A selection of user-definable alarms may be utilized to monitor the process, solution, or reactor
weights if balances are connected to monitor them and the measured pressure for one to three of the
connected pressures. All the alarms may be disabled or enabled and set to interlock and even provide an
audible alarm.

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Volume Flow Programming
From the main screen:
• Choose SETTINGS
• Select TUBING
• Confirm Motor RPM and head in the Tube Settings
• Select the TUBE SIZE from the drop down, press SET
Steps to enter a Volume Flow Recipe:
• Return to the main screen
• Select the RECIPES button
• Choose an existing recipe, or click on CREATE NEW (For this Quick Start, click on CREATE NEW)
• Click VOLUME FLOW

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New Volume Flow Recipe screen:
This screen allows you to add new steps and/or edit and delete existing steps; access process alarms for
editing and settings; Exit without a save or save and exit for prompts to save the recipe name. (The recipe
name is limited to upper- and lower-case letters, numbers and dashes).
• Select INSERT STEP BELOW to get started
• Press VOLUME FLOW RATE
NOTE: ‘Start’ and ‘End’ parameters are always listed and cannot be edited or deleted. Steps cannot be
inserted below ‘End’.
Configure a Volume Flow Rate & Time Step:
• Choose CONSTANT or INTERPOLATE
(An interpolated rate will ramp up from an initial rate to the new rate over the set time interval)
• Select the RATE field, enter desired flow rate, and ENTER

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Set a time for the step:
• Click in the RUN TIME field, then enter time in hours, minutes and seconds
• Select SET to add your new Volume Flow Rate Step to the recipe
• Click SAVE AND EXIT
NOTE: The above recipe is incorrect as it does not start with a step flow rate. Highlight any of the steps and
edit or delete as needed.
Name recipe:
• Select SAVE RECIPE, place cursor in text field
• From the keyboard, type the recipe name & ENTER
• Hit ENTER again to save the recipe and have it added to the recipe list
Configure Recipe Alarms:
• Highlight the recipe and hit EDIT
• Select EDIT ALARMS & SETTINGS

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The following screen illustrates the setting of low and high Solution (pumping from) and Reactor (pumping to)
weight alarms and interlocks if scales are connected to monitor them. The choice of flow rate units is also
configured here, either mL/min (default) or L/min. If not used, disregard this screen.
• Select SET when alarms are complete
• Hit SAVE to keep recipe
• Return to recipe list, select recipe to run
• Choose EXECUTE
The following screens are now available:
The Volume Flow Run Screen shows the ongoing process.
• Hit PRIME to prime tubing lines, and select again to stop priming
• Select START to begin the process
• Once the process starts, you can select PAUSE to interrupt the process
(once Pause is activated it will switch to RESUME, select again to resume the process)
• Select STOP to end the process
If ALARMS is selected from this screen, the Alarm States window will appear. Select BACK to return to the
Run screen.
While this process is actively running, data is being sent and can be captured on SciDoc II software.
Refer to APPENDIX A for tubing dimensions chart and available flow rates based on tubing and motor size.

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Start-up: Mass Flow Metering into a Bioreactor
EQUIPMENT
You will need the following items to get started:
Parker P/N Description Quantity
CHEM2-21 ChemTec II, CP-120 w/ 1081 Tandem Peristaltic Head, 160rpm Motor 1 pc
100-VIPER6 Mettler Toledo ICS425 Scale, 6000gm x.1gm 1 pc
400-116 Silicone Tubing, Platinum Cured, #16 25 ft (1 pkg)
080-072ICS Cable, Interfaces ChemTec II and Mettler Scale 1pc
080-USB RS232 to USB Adapter Cable 1 kit
N/A Appropriate Media Reservoir 1 pc
N/A Appropriate Bioreactor or Fermentor 1 pc
Hardware Setup
1. Unpack all the components, visually identify and inspect for damage.
2. At the bench, place the scale with the media reservoir to the far left. To the right of the bench, position
the ChemTec II and Bioreactor. Leave space between these items to allow for cables and tubing.
3. Connect the interface cable between the ChemTec II and the scale, connecting it to the “S1” connector on
the rear panel of the ChemTec II.
4. Connect the RS232 to USB cable between the PC and the “Printer” connector on the rear of the ChemTec
II. This cable may require a driver installation from the internet, and assistance from your internal IT
department to download.
5. Plug in to power equipment.
6. Install SciDoc II software from https://discover.parker.com/pump-support-gen2. Choose ChemTec II
from the menu, select the appropriate COM Port, and it will be ready to receive data from the pump.
7. If the ChemTec II and scale were purchased together from Parker, both will be configured to
communicate with each other. If purchased separately, contact Parker Technical Support
([email protected]) for assistance.
8. Cut an appropriate length of #16 tubing and connect it to the Media reservoir. Route the tubing from the
reservoir to the ChemTec II, open the head by rotating the lever 180 degrees counter-clockwise, and
place the tubing over the upper set of rollers. Confirm that the tubing is under the centering springs and
close the head by rotating the lever back to its original position. Connect the remaining end to the
Bioreactor.
This completes the hardware and tubing configuration.
PROGRAM EDITING AND EXECUTION
At this point, consider the parameters of the reaction being fed and determine the type of metering needed.
This can be done at a constant rate, a linear rate, or an exponential rate by using several short linear ramps.
Several user-definable alarms may be utilized to monitor the process; solution or reactor weights if balances
are connected to monitor them and the measured pressure for one to three of the connected pressures. All
the alarms may be disabled or enabled and set to interlock and provide and audible alarm.

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Mass Flow Programming
From the main screen:
• Choose SETTINGS
• Select TUBING
• Confirm Motor RPM and head in the Tube Settings
• Select the TUBE SIZE from the drop down, press SET
Steps to enter a Mass Flow Recipe:
• Return to the main screen
• Select the RECIPES button
• Choose an existing recipe, or click on CREATE NEW (For this Quick Start, click on CREATE NEW)
• Click MASS FLOW