Leica CV5030 User manual

Instructions for Use
Leica CV5030
Robotic Coverslipper
Leica CV5030 V 3.3, English 04/2019
Order No.: 14 0478 80101 RevK
Always keep this manual with the instrument.
Read carefully before working with the instrument.

3
Leica CV5030 – Robotic Coverslipper
The information, numerical data, notes and value
judgments contained in this manual represent
the current state of scientific knowledge and
state-of-the-art technology as we understand it
following thorough investigation in this field.
We are under no obligation to update the present
manual periodically and on an ongoing basis ac-
cording to the latest technical developments, nor
to provide our customers with additional copies,
updates etc. of this manual.
To the extent permitted in accordance with
the national legal system as applicable in each
individual case, we shall not be held liable for
erroneous statements, drawings, technical illus-
trations etc. contained in this manual. In particu-
lar, no liability whatsoever is accepted for any
financial loss or consequential damage caused
by or related to compliance with statements or
other information in this manual.
Statements, drawings, illustrations and other
information regarding the contents or technical
details of the present Instructions for Use are
not to be considered warranted characteristics
of our products.
These are determined only by the contract
provisions agreed between ourselves and our
customers.
Leica reserves the right to change technical
specifications as well as manufacturing process-
es without prior notice. Only in this way it is pos-
sible to continuously improve the technology and
manufacturing techniques used in our products.
This document is protected under copyright laws.
All copyrights to this documentation are held by
Leica Biosystems Nussloch GmbH.
Any reproduction of text and illustrations (or of
any parts thereof) by means of print, photocopy,
microfiche, web cam or other methods—includ-
ing any electronic systems and media—requires
express prior permission in writing by Leica
Biosystems Nussloch GmbH.
For the instrument serial number and year of
manufacture, please refer to the nameplate on
the back of the instrument.
© Leica Biosystems Nussloch GmbH
NOTE
Leica Biosystems Nussloch GmbH
Heidelberger Str. 17 - 19
D-69226 Nussloch
Germany
Phone: [phone]
Fax: [phone]
Internet: http://www.LeicaBiosystems.com

4Instructions for Use V 3.3 RevK – 04/2019
Contents
1. Important Information ....................................................................................................7
1.1 Symbols and their meanings....................................................................................................... 7
1.2 User group ..................................................................................................................................... 9
1.3 Intended use of instrument......................................................................................................... 9
1.4 Instrument type............................................................................................................................. 9
2. Safety ..............................................................................................................................10
2.1 Safety notes................................................................................................................................. 10
2.2 Warnings...................................................................................................................................... 10
3. Instrument Components and Specifications ...........................................................13
3.1 Overview - instrument components ........................................................................................ 13
3.2 Technical data............................................................................................................................. 14
3.3 Standard delivery—packing list............................................................................................... 15
4. Instrument Setup...........................................................................................................17
4.1 Installation site requirements................................................................................................... 17
4.2 Unpacking the CV5030 ............................................................................................................... 18
4.2.1 Setting up the CV5030 ................................................................................................................ 20
4.3 Preparing and adjusting the instrument ................................................................................. 20
4.3.1 Removing or installing the transport anchors........................................................................ 21
4.4 Leveling the instrument ............................................................................................................. 22
4.5 Exhaust system ........................................................................................................................... 22
4.6 Installing the dispenser group.................................................................................................. 24
4.7 Aligning the dispenser needle height relative to the specimen slide outfeed................. 26
4.8 Dispenser needle cleaner (nozzle cleaner)............................................................................ 29
4.9 Connecting the power supply................................................................................................... 32
4.10 Installing the accessories......................................................................................................... 32
4.11 Refilling consumables................................................................................................................ 34
5. Operation........................................................................................................................36
5.1 Control panel functions.............................................................................................................. 36
5.2 Key functions for instrument operation .................................................................................. 37
5.3 Switching the instrument on or off .......................................................................................... 39
5.4 Brief inspection before starting the coverslipping operation............................................. 41
5.5 The coverslipping operation..................................................................................................... 42
5.6 Interrupting the coverslipping operation................................................................................ 44
5.7 Display indicators and instructions......................................................................................... 50
5.8 Button functions for programming........................................................................................... 56

5
Leica CV5030 – Robotic Coverslipper
Contents
5.9 Setting parameter sets .............................................................................................................. 57
5.10 Menu A – parameter settings................................................................................................... 57
5.11 Menu B – parameter settings................................................................................................... 60
5.11.1 Leaving the parameter and submenu...................................................................................... 62
5.12 Recommendation for parameter setting (beginning with firmware 3.01.04) ................... 63
5.13 Determining the optimum parameter setting (menu A+B)................................................... 66
5.13.1 Procedure .................................................................................................................................... 66
6. Workstation operation.................................................................................................72
6.1 Operation as ST5010 – CV5030 workstation........................................................................... 72
6.2 Operation as ST5020 – CV5030 workstation........................................................................... 74
6.3 Important instructions for operation as workstation............................................................ 76
6.4 Interrupting workstation operation.......................................................................................... 78
7. Cleaning and Maintenance ........................................................................................79
7.1 Notes on cleaning and maintenance ...................................................................................... 79
7.2 Daily cleaning and maintenance - overview.......................................................................... 80
7.3 Weekly cleaning and maintenance......................................................................................... 81
7.4 Cleaning and maintenance as necessary .............................................................................. 82
7.5 Description of the required daily cleaning measures .......................................................... 82
7.5.1 Loading chute and bath transport with transport chain ...................................................... 82
7.5.2 Dispenser needle cleaner (nozzle cleaner)............................................................................ 82
7.5.3 Glass vial in the dispenser rest position................................................................................. 83
7.5.4 Loading bath................................................................................................................................ 83
7.5.5 Dispenser needles...................................................................................................................... 83
7.5.6 Cover slip catch tray .................................................................................................................. 83
7.5.7 Cover slip magazine ................................................................................................................... 83
7.5.8 Skids of the Pick & Place module............................................................................................ 83
7.5.9 Cleaning and replacing the suction cups............................................................................... 84
7.5.10 Cover slip sensor ........................................................................................................................ 84
7.5.11 Specimen slide outfeed............................................................................................................. 84
7.6 Description of the required weekly cleaning measures...................................................... 85
7.6.1 Dispenser group.......................................................................................................................... 85
7.6.2 Dispenser needle cleaner (nozzle cleaner)............................................................................ 86
7.6.3 Specimen slide holder, gripper and output magazines........................................................ 86
7.7 Description for cleaning and maintenance as necessary................................................... 87
7.7.1 Active carbon filter..................................................................................................................... 87
7.7.2 Discharge chute of the TS5015 or TS5025 Transfer Station for workstation operation . 87

6Instructions for Use V 3.3 RevK – 04/2019
Contents
7.7.3 Transfer arm of the TS5015 or TS5025 Transfer Station for workstation operation........ 87
7.8 Procedure for changing the cover slip mountant ................................................................. 88
7.8.1 Changing from one xylene-based coverslip mountant to another..................................... 88
7.8.2 Changing from a xylene substitute coverslip mountant to a xylene-based mountant.... 88
7.8.3 Changing from a xylene-based coverslip mountant to a xylene substitute...................... 88
8. Malfunctions and Troubleshooting...........................................................................89
8.1 Error codes .................................................................................................................................. 89
8.2 Troubleshooting.......................................................................................................................... 91
9. Optional Accessories ..................................................................................................95
9.1 Ordering information.................................................................................................................. 95
10. Warranty and Service................................................................................................106
11. Decontamination Certificate (master) ....................................................................107
Appendix A Application-related notes and recommendations...................................109
A1.1 Leica specimen slide holders, output and coverslip magazines made of plastic ......... 109
A1.2 Specimen slide holders from other manufacturers............................................................ 110
A1.3 Specimen slides and gripper mechanism ............................................................................ 111
A1.4 CV5030 – Validated and recommended specimen slides .................................................. 111
A1.5 Cover slips.................................................................................................................................. 113
A1.6 Labels for specimen slides...................................................................................................... 114

7
Leica CV5030 – Robotic Coverslipper
1. Important Information
1.1 Symbols and their meanings
(5)
START
Manufacturer
In vitro diagnostics (IVD) medical device
This product fulfills the requirements of
the Council's Directive 98/79/EC con-
cerning in vitro diagnostics (IVD) medi-
cal devices.
The CSA test mark means that a product
has been tested and fulfills the appli-
cable safety and/or performance stan-
dards, including the relevant standards
defined or administered by the American
National Standards Institute (ANSI),
Underwriters Laboratories (UL), the
Canadian Standards Association (CSA),
the National Sanitation Foundation Inter-
national (NSF) and others.
Environmental protection symbol of the
China RoHS directive. The number in
the symbol indicates the "Environment-
friendly Use Period" of the product. The
symbol is used if a substance restricted
in China is used in excess of the maxi-
mum permitted limit.
Symbol for labeling electrical and elec-
tronic equipment in accordance with
Section 7 of the German Electrical and
Electronic Equipment Act (ElektroG). Ele-
ktroG is the law regarding the sale, re-
turn and environmentally sound disposal
of electrical and electronic equipment.
Warnings
appear in a gray box and are marked by
a warning triangle .
Notes
i.e. important user information appear
in a gray box and are marked by an in-
formation symbol .
Inflammable solvent and reagents are
marked with this symbol.
Instrument surfaces which become hot
during operation are marked with this
symbol.
Avoid direct contact to prevent risk of
burning.
Numbers and parentheses refer to item
numbers in the illustrations.
Function keys to be pressed on the in-
strument control panel are written in
bold-print capital letters.
Date of Manufacture

8Instructions for Use V 3.3 RevK – 04/2019
1. Important Information
1.1 Symbols and their meanings
REF
SN
Order No.
Serial number
Observe the Instructions for Use
The package contents are fragile and
must be handled with care.
Indicates the correct upright position of
the package.
The package must be kept in a dry en-
vironment.
It is not permitted to stack packages,
and no loads may be placed on top of
the package.
Indicates the temperature
range to which the medical
device can be safely ex-
posed.
Minimum –29 °C
Maximum +50 °C
Indicates the air humidity
range to which the medical
can be safely exposed.
Minimum 10 %
Maximum 85 %
Example of labeling
in accordance with
IPPC
Package labeling in accor-
dance with German Hazard-
ous Freight Ordinance Road
and Rail (GGVSE)/European
Agreement concerning the
International Carriage of
Dangerous Goods by Road
(ADR) for transporting haz-
ardous goods.
Class 3: "FLAMMABLE
LIQUID"
Tip-n-Tell checks whether
the shipment was transport-
ed upright and stored as you
prescribed. With a pitch of
60° or more, the blue quartz
sand flows into the arrow-
shaped indicator window
and sticks there permanent-
ly. Any improper handling of
the shipment is immediately
and definitively detectable.
• IPPCsymbol
• Countrycodein accordance with ISO3166,
e.g. DE for Germany
• Regionalidentifier,e.g.HEforHessen
• Producer/treatmentprovidercode,unique
assigned number starting with 49
• Treatmentcode,e.g.HT(heattreatment),MB
(methyl bromide), and possibly DB (debarked)

9
Leica CV5030 – Robotic Coverslipper
1.2 User group
• TheLeicaCV5030maybeoperatedbytrained
laboratory personnel only.
• Alllaboratorypersonneldesignatedtooperate
this instrument must read these Instructions
for Use carefully and must be familiar with all
technical features of the instrument before
attempting to operate it.
Fig. 1
1.3 Intended use of instrument
The Leica CV5030 is a robotic coverslipper for
coverslipping tissue sections, cells or swabs
mounted on specimen slides with cover slips
made out of glass using a wide variety of differ-
ent cover slip mountants. It may only be used
with instrument accessories approved by Leica
Biosystems Nussloch GmbH.
1.4 Instrument type
All information provided in these Instructions for
Use applies only to the instrument type indicated
on the cover page.
A nameplate indicating the instrument serial
number is attached to the rear side of the in-
strument. (The serial number is also displayed
above the loading door on the front side of the
instrument.)
1. Important Information
Any use of the instrument other than
its designated use is considered im-
proper.
Failure to adhere to these instructions
may result in an accident, personal
injury, damage to the instrument or ac-
cessory equipment.
Proper and intended use includes
compliance with all inspection and
maintenance instructions, along with
the observance of all instructions in
the Instructions for Use.
Fig. 1 is provided as an example only
and shows a valid nameplate for this
instrument with the necessary in-
formation about instrument type and
power requirement. The precise data
for the various versions is specified in
Chapter 3.2 "Technical data".

10 Instructions for Use V 3.3 RevK – 04/2019
2. Safety
These Instructions for Use include important instruc-
tions and information related to the operating safety
and maintenance of the instrument.
The Instructions for Use are an important part of the
product, and must be read carefully prior to startup
and use and must always be kept near the instrument.
2.2 Warnings
The safety devices installed in this instrument by the manufacturer only constitute the basis for accident
prevention. Operating the instrument safely is, above all, the responsibility of the owner, as well as the
designated personnel who operate, service or repair the instrument.
To ensure trouble-free operation of the instrument, make sure to comply with the following instructions
and warnings.
Please note that electrostatic charge may result through direct or indirect contact with the Leica CV5030.
This instrument was built and tested in accordance
with the safety regulations for electrical measuring,
control, regulating and laboratory devices.
To maintain this condition and ensure safe operation,
the user must observe all notes and warnings con-
tained in these Instructions for Use.
2.1 Safety notes
These Instructions for Use must be ap-
propriately supplemented as required
by the existing regulations on accident
prevention and environmental safety in
the operator's country.
The instrument's CE certificate can be
found on the Internet at:
http://www.LeicaBiosystems.com
• The safety and caution notes in this chapter must be observed at all times.
• Be sure to read these notes even if you are already familiar with the operation and use of
other Leica products.
• The protective devices on the instrument and its accessories must not be removed or modi-
fied. Only qualified service personnel authorized by Leica may repair the instrument and
access its internal components.
Residual risks
• The instrument has been designed and constructed with the latest state-of-the-art technol-
ogy and according to recognized standards and regulations with regard to safety technology.
Operating or handling the instrument incorrectly can place the user or other personnel at
risk of injury or can cause damage to the instrument or other property. The instrument may
be used only as intended and only if all of its safety features are in proper working condition.
Malfunctions which could impede safety must be remedied immediately.
• Only original spare parts and permitted original accessories may be used.

11
Leica CV5030 – Robotic Coverslipper
Safety instructions - transport and installation
Safety instructions - working with the instrument
2. Safety
• The instrument must be transported in an upright position only (use transport anchors!).
• Two persons are required when lifting or carrying the instrument!
• The Leica CV5030 is intended for use in enclosed rooms only.
• The instrument may be operated with the provided power cable only. This power cable may
not be replaced by another. Should the provided power cable not fit in the socket at the in-
stallation location, notify the responsible Leica Service.
• Only connect the instrument to a grounded power socket. The protective effect may not be
eliminated by an extension cable without a protective grounding conductor. The instrument
automatically recognizes the applied voltage/frequency.
• The installation location must be well ventilated, and must contain no sources of ignition
of any kind. The chemicals to be used in the Leica CV5030 are highly flammable as well as
hazardous to health.
• The instrument may not be operated in hazardous locations.
• Condensation water may form in the instrument if there is an extreme difference in tempera-
ture between the warehouse and the installation site and if air humidity is high at the same
time. If this is the case, wait at least two hours before switching on the instrument. Failure to
comply with this may cause damage to the instrument.
• The instrument must be leveled carefully before commissioning (for more information, refer to
Chapter 4.5, "Instrument Setup").
• The instrument may only be operated by trained laboratory personnel.
• It must only be operated for the purpose of its designated use and according to the instruc-
tions contained in these Instructions for Use.
• In the event of an emergency, switch off the power switch and unplug the instrument from
the power supply.
• Suitable protective clothing (lab coat, gloves, protective goggles) must be worn when work-
ing with reagents. Avoid skin contact with solvents or cover slip mountants.
• Make sure that mountant is applied in the correct amount (for additional information, refer
to Chapter 5.10 - Menu A - Parameter settings). Excess mountant can run from the specimen
slide onto the work surface and the transport belt of the bath insert, thus impairing the move-
ment of parts of the instrument (refer also to Chapter 7 - Cleaning and Maintenance).
• During operation, do not block motor-driven components with objects or manual interfer-
ence. There is a risk of injury from broken glass!
• Do not carry out the discarding movement of the Pick & Place module (cover slip mount)
manually! Please observe the notes in Chapter 4.7.1.
• Never leave the instrument unattended for a long period of time. Particular care must be tak-
en during a power failure to ensure that tissue sections do not dry out.
• Remove all glass parts or other objects away from the CV5030 working area during STOP.
Only then may START be actuated.
2.2 Warnings (continued)

12 Instructions for Use V 3.3 RevK – 04/2019
Hazards - servicing and cleaning
2. Safety
Warnings - Handling reagents
Safety instructions - working with the instrument (continued)
• Operate the instrument with the exhaust hose and connection on an external laboratory
extraction or under a suitable fume hood. In the process, the corresponding active carbon
filter should be used for auxiliary support.
• Since the instrument is intended to be operated with a solvent, there is a fire hazard if
work with an exposed flame (e.g. Bunsen burner) is carried out in the direct vicinity of the
instrument.
• Ensure that no liquids come into contact with the electronics during work.
• Take care when handling solvents and coverslip mountants!
• Always wear rubber gloves, a lab coat and safety goggles when handling the chemicals
used in this instrument.
• The reagents used can be both toxic and/or flammable.
• Dispose of used reagents while observing applicable local regulations and the disposal
regulations of your company/lab.
• Before each maintenance task, remove the loading bath and the specimen slide holder from
the instrument, switch the instrument off and unplug it from the power supply.
• Only Leica service technicians are authorized to open the instrument for maintenance and
repair work.
• When using cleaners, please comply with the safety instructions of the manufacturer and the
laboratory safety regulations.
• When cleaning the instrument surfaces, do not use scouring powders or solvents containing
acetone, chlorine or xylene.
• Clean the lid and the housing with mild and pH-neutral commercial household cleaners.
Aggressive cleaning agents and solvents can damage the lacquered surfaces!
• Ensure that no liquids come into contact with the electronics during cleaning.
Material safety data sheets for reagents can be requested from the respective manufacturer of
the chemical.
Alternatively, the material safety data sheets can be downloaded from the following website:
http://www.msdsonline.com

13
Leica CV5030 – Robotic Coverslipper
3. Instrument Components and Specifications
3.1 Overview - instrument components
Unit cover
Main switch
Control panel
Output station for out-
put magazines
Bottle for cover-
slip mountant
Input door
Height-adjustable instrument
feet
Maintenance
door
Output magazines
Cover slip
magazine
Dispenser rest
(park) position
(prime position)
Fig. 2
Loading bath
Dispenser group
Pick & Place
module (cover
slip mount)
Loading drawer

14 Instructions for Use V 3.3 RevK – 04/2019
3. Instrument Components and Specifications
3.2 Technical data
Nominal supply voltages: 100 - 240 V AC, ± 10 %
Nominal frequency: 50 - 60 Hz
Approvals CE, CSA C/US
Fuse: Automatic fuseT5A
Nominal power: 100 VA
Dimensions (W x H x D): Hood closed: 420 x 600 x 550 mm
Hood opened: 420 x 980 x 550 mm
Width (from the left to the right base): 370 mm
Depth (from the posterior base to the front base): 525 mm
Multistainer workstation: Hood opened: 1620 x 980 x 760 mm
Weight (without packaging material): approx. 57 kg
Net weight (including packaging material): approx. 104 kg
Operating temperature range: +15 °C - +35 °C
Storage temperature range: –29 °C - +50 °C
Transport temperature range: –29 °C - +50 °C
Relative humidity: Maximum 85 % (non-condensing)
IEC 1010 classification: Protection class 1
Pollution degree 2
Overvoltage installation category II
International protection class: IP20
Operating elevation: Up to a max. of 2000 m above sea level
A-weighted noise level: <65 dB(A), measured in 1 m target range
Sockets RS 232C, service interface
Uninterruptible power supply (UPS): The uninterruptible power supply (UPS) should be
designed for a capacity of at least 200 VA over a
time frame of 5 minutes.
Heat dissipation: 100 J/s
Exhaust air:
Hose material EVA (ethylene vinyl acetate)
Hose length: 3000 mm
Hose diameter: 32 mm
Hose circumference: 41 mm
Exhaust air quantity: 38.5 m3/h
Extraction: Active carbon filter and extraction hose for con-
necting to an external extraction device

15
Leica CV5030 – Robotic Coverslipper
3. Instrument Components and Specifications
3.3 Standard delivery—packing list
Performance:
Specimen slide throughput: 1 specimen slide in approx. 9 sec.
Usable specimen slides: All commercially available specimen slides per
ISO standard 8037-1. Leica recommends the use of
validated Surgipath™ specimen slides.
Cover slip magazine capacity: Dependent on thickness of the cover slip:
120 (22-24 mm x 60 mm; #1.5)
160 pcs. (22-24 mm x 40 mm; #1.0)
Cover slips: 22-24 mm x 40 - 60 mm; #1.0 or #1.5
Leica recommends the use of validated Surgipath™
ASC cover slips or Surgipath™ Premier Cover
Glass cover slips.
Mountant bottle capacity: 250 ml
Max. fill volume: 200 ml
Coverslip mountant application quantity: Individually configurable
Mountant types: See Chapter 5.12
Specimen slide holders: Leica specimen slide holders (20 or 30 specimen
slides) and other specimen slide holders (refer to
Chapter 9 - "Optional Accessories")
Output magazines: Capacity of 20 or 30 specimen slides (up to
60 specimen slides)
3.2 Technical data (continued)
The standard equipment for the Leica CV5030 includes the following parts: Order number
1 Basic instrument 14 0478 39700
1 Dispenser group, consisting of: 14 0478 39402
1 Dispenser
2 Dispenser needles, 21 G 14 0478 40157
2 Dispenser needles, 20 G 14 0478 40158
2 Dispenser needles, 18 G 14 0478 40159
2 Dispenser needles, 16 G 14 0478 40160

16 Instructions for Use V 3.3 RevK – 04/2019
Carefully check the delivery against the packing list and the delivery note. Should you find any
discrepancies, please contact your Leica sales office without delay.
3. Instrument Components and Specifications
1 Accessory kit, consisting of: 14 0478 39734
1 Leica brush 14 0183 30751
1 Allen key, No. 3.0 14 0222 04138
1 Screwdriver 5.5 x 150 14 0170 10702
1 Active carbon filter (xylene) 14 0422 30673
1 Dispenser needle cleaner, assembly 14 0478 40941
2 Glass bottles with lids, for coverslip mountant, 250 ml 14 0464 36537
1 Package of 5 pcs. of 30 specimen slide holder, plastic 14 0475 33643
1 Cover for loading bath 14 0478 39584
1 Cover slip catch tray 14 0478 39585
1 Package of 4 pcs. of 30 output magazine 14 0478 39586
1 Loading bath for specimen slide, deep 14 0478 39657
1 Bath insert for Leica 30 specimen slide holder 14 0478 39593
1 Package of 2 pcs. suction cups 14 0478 39701
2 Cover slip magazines, Multi-size™40-60 x 22 mm 14 0478 39748
2 Cover slip magazines, Multi-size™40-60 x 24 mm 14 0478 39749
1 Glass vial, 12 ml 14 0478 39789
1 Exhaust hose, 3 m 14 0478 39820
1 Instructions for Use, printed (English), for Leica CV5030 14 0478 80001
1 Language CD-ROM 14 0478 80200
The country specific power cord needs to be ordered separately. Please find a list of all power cords
available for your device on our website www.LeicaBiosystems.com within the product section.
3.3 Standard delivery—packing list (continued)

17
Leica CV5030 – Robotic Coverslipper
4.1 Installation site requirements
4. Instrument Setup
The location for the Leica CV5030 Robotic Coverslipper must meet the following requirements:
• Theinstrumentrequiresaninstallationareaofapprox.420x600mm.
• Thetablemusthaveasufficientloadcapacityandrigiditywithrespecttotheweightoftheinstrument.
• Theinstrumentisdesignedforindooruseonly.
• Thepowersupplymustbeatadistancenogreaterthanthelengthofthepowercable;donot
connect an extension cable.
• TheinstrumentMUST be connected to a grounded socket.
• Useonlyoneoftheprovidedpowercablesthatisintendedforthelocalpowersupply.
• Theinstrumentmustnotbesetupunderanair-conditioningsystem.
• Avoidimpacts,directsunlightandexcessivecurrentfluctuations.
• Thechemicalsusedintheinstrumentareeasilyinflammableandposeahealthhazard.
• AllofthedeviceconnectionsarelistedintheInstructionsforUse.
• We recommend operating the robotic coverslipper with an exhaust hose (max. length of the
exhaust hose: 3.00 m) and connection to external laboratory extraction or under a suitable fume
hood. The instrument should be operated with the associated active carbon filter in the process.
• The installation location must be well ventilated, and must contain no sources of ignition of
any kind.
• The chemicals used in the Leica CV5030 are easily inflammable and pose a health hazard.
• Never operate the instrument in rooms with an explosion hazard.
• Condensation water may form in the instrument if there is an extreme difference in tempera-
ture between the storage location and the installation site and if air humidity is high at the
same time. If this is the case, wait at least two hours before switching on the instrument.
• Failure to adhere to this waiting period may result in damage to the instrument.
• To ensure proper function of the instrument, it must be set up while maintaining a minimum
clearance of 10 cm between the right side or rear panel of the instrument and walls or fix-
tures. Maintain a clearance of 25 cm between the left side and walls or fixtures to ensure
unimpeded access to the service door.
• The instrument must be set up so that the power supply at the rear panel of the instrument
and the power plug can be reached at all times.
• The installation location must be protected against electrostatic discharges.

18 Instructions for Use V 3.3 RevK – 04/2019
4.1 Installation site requirements (continued)
4. Instrument Setup
• TheinstrumentoperatorhastoensurethatESDsafetyprecautionsaremaintained.
• Theinstrumentoperatorisobligatedtoconformtothelocalworkplacelimitvaluesandtodocument
them.
Furthermore, the instrument operator must ensure that there is sufficient air exchange and the
active carbon filter is changed at the recommended interval.
The instrument operator bears responsibility for complying with workplace limits and the measures
necessary for this, including documentation.
4.2 Unpacking the CV5030
Fig. 3
1
2
3
4
7
Opening the package (Fig. 3)
• Unscrewthe8screws(Fig. 3,2) on the sides
of the wooden box and loosen the cover.
• Carefullyliftthecoverfromthewoodenbox.
When the instrument is delivered, check the tilt indicators on the pack-
aging. If the arrowhead is blue, the shipment was transported laying
flat, was tilted at too great an angle or fell over during transport.
Note this on the shipping documents and check the shipment for
possible damage.
Only personnel authorized by Leica may unpack and install the instrument.

19
Leica CV5030 – Robotic Coverslipper
Removing the accessories (Fig. 4)
• Removethetwoscrews(Fig. 3, 4) in the side
panel (left and right) and take out the transport
anchor (5).
• The box withaccessories(6) can now be
removed from the shipping package.
Fig. 4
5
6
7
4. Instrument Setup
4.2 Unpacking the CV5030 (continued)
Removing the instrument
• Unscrewthe8screws(Fig. 3,3) on the bottom
of the wooden box on the exterior. Carefully
remove the wooden box from the baseplate.
• Unscrew2x8screws (front and rear on the
instrument, (8) in Fig. 5), loosen and remove the
retaining clips (9) from the baseplate.
• Removethedustcoverfromtheinstrument.
For setting up the instrument, refer to
Chapter 4.2.1 - Setting up the CV5030.
Fig. 5
8
99

20 Instructions for Use V 3.3 RevK – 04/2019
• Removethetransportanchors.
• Insertthefilterandattachtheexhausthose.
• Leveltheinstrument.
• Installthedispensergroup.
• Alignthedispenserneedlewiththespecimen
slide outfeed.
• Installthedispenserneedlecleaner.
• Connectthepowersupply.
4. Instrument Setup
• Grabholdofbottomofthe instrument from
the front and rear (with at least 2 people; the
instrument weighs approx. 57 kg) and place it
on a stable laboratory table.
• Whendoingso,ensurethattheinstrumentis
standing on all four feet.
• Pulltheplasticprotectivehoodoffofthein-
strument by pulling upwards and remove the
two adhesive strips (20).
• Removethefoamsafeguard(21) from the
output station.
• Opentheloadingdoor(65) and remove the
foam cover for the loading bath.
• Ensurethattheprovidedaccessoriesare
complete in accordance with the order.
Fig. 6
4.3 Preparing and adjusting the instrument
20
21
• Usethefollowingaccessories:
- Mountant bottle
- Cover slip catch tray
- Cover slip magazine
- Output magazine
- Loading bath
- Dispenser needle cleaner
- Glass vial for dispenser rest position
- Refill consumables
65
To commission the instrument, carry out the following tasks described in the chapters below:
4.2.1 Setting up the CV5030