Agilent Technologies 7200 Operating manual

Agilent Technologies
Agilent 7200
Accurate-Mass/Q-TOF
GC/MS System
Troubleshooting and
Maintenance Manual

2 Troubleshooting and Maintenance Manual
Notices
© Agilent Technologies, Inc. 2012, 2014
No part of this manual may be reproduced in
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Manual Part Number
G3850-90009
Edition
First Edition, August 2014
Printed in USA
Agilent Technologies, Inc.
5301 Stevens Creek Boulevard
Santa Clara, CA 95051
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Safety Notices
CAUTION
A CAUTION notice denotes a
hazard. It calls attention to an
operating procedure, practice, or
the like that, if not correctly
performed or adhered to, could
result in damage to the product or
loss of important data. Do not
proceed beyond a CAUTION notice
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fully understood and met.
WARNING
A WARNING notice denotes a
hazard. It calls attention to an
operating procedure, practice, or
the like that, if not correctly
performed or adhered to, could
result in personal injury or death.
Do not proceed beyond a
WARNING notice until the
indicated conditions are fully
understood and met.

Troubleshooting and Maintenance Manual 3
Contents
1 Introduction
Abbreviations Used 8
The 7200 Accurate-Mass Quadrupole Time-of-Flight GC/MS
System 10
7200 Accurate-Mass Q-TOF GC/MS Description 12
Side Panel AC Power Connectors 13
Back Panel Connectors 14
Interfacing Start Events to External Devices 15
Remote control processor 15
Remote start signals 15
System ready 15
Start run input 16
Important Safety Warnings 17
Safety and Regulatory Certifications 20
Intended Use 23
Cleaning/Recycling the Product 23
Moving or Storing the MS 23
2 General Troubleshooting
Troubleshooting Tips and Tricks 26
General Symptoms 27
Chromatographic Symptoms 29
Mass Spectra General Symptoms 34
Pressure Symptoms 36
Temperature Symptoms 38

4 Troubleshooting and Maintenance Manual
Common Types of Errors 40
Air Leaks 45
Contamination 46
3 CI Troubleshooting
Common CI-Specific Problems 50
Troubleshooting Tips and Tricks 51
Air Leaks 52
Pressure-Related Symptoms 55
Signal-Related Symptoms 58
Tuning-Related Symptoms 64
The CI ion source is dirty 65
Air leak 65
4 General Maintenance
Before Starting 68
Scheduled maintenance 68
Tools, spare parts, and supplies 69
High voltage precautions 69
Dangerous temperatures 69
Chemical residue 70
Electrostatic discharge 71
To Refill the EI Calibration Vial 72
Materials needed 72
Refill 72
To Refill the IRM Vial 74
Materials needed 74
Procedure 74
To Connect the GC Nitrogen Gas Source to the Collision Cell 76

Troubleshooting and Maintenance Manual 5
Materials needed 76
Procedure 76
To Replace the Seals in the RIS Probe 77
Materials needed 77
Procedure 77
To Separate the GC from the MS 79
Materials needed 79
Procedure 79
To Position the GC Next to the MS 82
Procedure 82
To Move or Store the MS 83
Materials needed 83
Procedure 83
To Access the Left Side Lifting Handle 86
Materials needed 86
Procedure 87
5 CI Maintenance
To Minimize Foreline Pump Damage from Ammonia 90
To Replace the Methane/Isobutane Gas Purifier 91
To Clean the Reagent Gas Supply Lines 92
To Refill the CI Calibration Vial 93
Materials needed 93
Refill 93
6VacuumSystem
Overview 96
Maintaining the Vacuum System 97
Periodic maintenance 97
Other procedures 97

6 Troubleshooting and Maintenance Manual
Vacuum System Components 97
Common Vacuum System Problems 98
Foreline Pump 99
To check the oil mist filter 99
To check the foreline pump fluid level 100
To add foreline pump fluid 100
To replace the foreline pump fluid 101
Side Plate 104
Vacuum Seals 104
Calibration Valves 105
EI Calibration Valve 105
CI Calibration Valve 106
IRM Calibration Valves 107
7ReplacementParts
To Order Parts 110
Electronics 111
Vacuum System 116
Analyzer 121
RIS Manifold 130
GC/MS Interface 132
Consumables and Maintenance Supplies 133

7
Agilent 7200 Accurate-Mass Q-TOF GC/MS System
Troubleshooting and Maintenance Manual
Agilent Technologies
1
Introduction
Abbreviations Used 8
The 7200 Accurate-Mass Quadrupole Time-of-Flight GC/MS System 10
7200 Accurate-Mass Q-TOF GC/MS Description 12
Side Panel AC Power Connectors 13
Interfacing Start Events to External Devices 15
Important Safety Warnings 17
Safety and Regulatory Certifications 20
Intended Use 23
Cleaning/Recycling the Product 23
Moving or Storing the MS 23
This section provides general information about the 7200 Accurate-Mass
Quadrupole Time-of-Flight (Q-TOF) GC/MS System, including a hardware
description and general safety warnings.

8 Troubleshooting and Maintenance Manual
1Introduction
Abbreviations Used
The abbreviations in Table 1 are used in discussing this product. They are
collected here for convenience.
Table 1 Abbreviations
Abbreviation Definition
AC Alternating current
ALS Automatic liquid sampler
BFB Bromofluorobenzene (calibrant)
CC Collision cell
CI Chemical ionization
DC Direct current
DFTPP Decafluorotriphenylphosphine (calibrant)
DIP Direct insertion probe
EI Electron impact
EPC Electronic pneumatic control
eV Electron volt
GC Gas chromatograph
id Inside diameter
IRM Internal Reference Mass
LAN Local Area Network
m/z Mass to charge ratio
MFC Mass flow controller
MS Mass spectrometer
MS1 Front quadrupole
NCI Negative chemical ionization
OFN Octafluoronaphthalene (sample)

Introduction 1
Troubleshooting and Maintenance Manual 9
PCI Positive chemical ionization
PFDTD Perfluoro-5,8-dimethyl-3,6,9-trioxydodecane (calibrant)
PFET 2,4,6-tris (Pentafluoroethyl)-1,3,5-triazine
PFTBA Perfluorotributylamine (calibrant)
Q-TOF Quadrupole time-of-flight
Quad Quadrupole mass filter
RF Radio frequency
RFPA Radio frequency power amplifier
TOF Time-of-flight
Torr Unit of pressure, 1 mm Hg
Turbo Turbomolecular vacuum pump
Table 1 Abbreviations (continued)
Abbreviation Definition

10 Troubleshooting and Maintenance Manual
1Introduction
The 7200 Accurate-Mass Quadrupole Time-of-Flight GC/MS
System
The 7200 Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) GC/MS System is
a standalone capillary GC detector for use with the Agilent 7890 Series gas
chromatograph. The 7200 Q-TOF features:
•Three turbomolecular vacuum pumps
•Rotary vane foreline pump
•Independently MS-heated EI or CI ion source
•Removable ion source (RIS) probe with bayonet and cooling chamber, which
allows quick change from EI to CI source with minimal loss of vacuum in
the instrument
•Independently MS-heated hyperbolic quadrupole mass filter, which can be
heated to high temperatures, minimizing the contamination typical with
low temperature analyses
•Single hexapole collision cell
•Vacuum-insulated flight tube with dual-stage ion mirror
•Fast electronics, allowing fast sampling rates
•Analog to digital detector
•Independently GC-heated GC/MS interface with automatic retraction
during source removal
Physical description
The 7200 Q-TOF GC/MS is approximately 48 cm high, 71 cm wide, and 89 cm
deep. The flight tube extends 84 cm up over the top of the instrument. The RIS
probe handle, when attached, extends 48 cm from the front of the instrument.
The weight of the instrument is 152 kg for the turbo pump mainframe. The
attached foreline (roughing) pump weighs an additional 22.2 kg.
The basic components of the instrument are: the frame/cover assemblies, the
vacuum system, the GC/MS interface, the removable ion source, the flight tube
electronics, the collision cell, the detector, and the analyzer.