Endress+Hauser Analytik Jena Biometra TSC ThermoShaker User manual

Biometra TSC ThermoShaker
Order No. 846-051-600 (230 V)
Order No. 846-051-690 (115 V)
Manual
846-9-990-031
Please read these instructions carefully
before using this apparatus!
Biometra GmbH
Service Department
Rudolf-Wissell-Str. 30 Rudolf-Wissell-Str. 14-16
D-37079 Göttingen D-37079 Göttingen
Germany Germany
Phone: +49 5 51 / 50 68 6-0 Phone: [phone], -12, -14
Fax: +49 5 51 / 50 68 6-66 Fax.: +49 5 51 / 50 88 1-11
E-mail: [e-mail] e-mail: [e-mail]
Internet: http://www.analytik-jena.com

Manual Biometra TSC ThermoShaker, Vers. 01_2019
1
1 Contents
1CONTENTS ....................................................................................................... 1
2SAFETY............................................................................................................. 2
2.1 DEFINITION OF SYMBOLS:.................................................................................. 2
2.2 SAFETY PRECAUTIONS ...................................................................................... 2
3SCOPE OF DELIVERY...................................................................................... 4
4ACCESSORIES................................................................................................. 5
5GENERAL INFORMATION ............................................................................... 6
6INSTALLATION................................................................................................. 7
6.1 UNPACK AND CHECK......................................................................................... 7
6.2 INSTALLATION................................................................................................... 7
6.3 INSTALLATION OF BLOCK MODULES................................................................... 7
6.4 CHANGING BLOCK MODULES............................................................................. 8
7OPERATION OF TSC THERMOSHAKER........................................................ 9
7.1 PARAMETER SETTING...................................................................................... 10
7.1.1 Reaction Time (TIME).......................................................................................10
7.1.2 Shaking Intensity (RPM)...................................................................................10
7.1.3 Reaction Temperature (T, ºC) .........................................................................10
7.1.4 Program Execution............................................................................................10
8CALIBRATION ................................................................................................ 12
8.1 CALIBRATION PROCEDURE............................................................................... 12
9MAINTENANCE............................................................................................... 14
9.1 CLEANING ...................................................................................................... 14
9.2 RUBBER BELT REPLACEMENT .......................................................................... 14
10 SPECIFICATIONS........................................................................................... 15
11 SERVICE ......................................................................................................... 17
11.1 DEVICE RETURN INFORMATION ......................................................................... 17
12 NOTE FOR DISPOSAL OF ELECTRIC/ELECTRONIC WASTE .................... 18
13 DECLARATION OF CONFORMITY................................................................ 19
Manual for apparatus with serial number 010143-1208-0106 or higher

Manual Biometra TSC ThermoShaker, Vers. 01_2019
2
2 Safety
2.1 Definition of Symbols:
Caution: Read these operating instructions fully before use and pay
particular attention to sections containing this symbol.
Caution: Surfaces can become hot during use.
Caution: Danger! High voltage!
Caution: Fragile!
2.2 Safety Precautions
General Safety:
Use only as specified by the operating instructions, or the intrinsic protection may
be impaired.
The unit should be saved from shocks or drops.
The unit must be stored and transported in a horizontal position (see packaging
labelling).
After transport or storage in humid conditions, dry out the unit before connecting it
to the supply voltage. During drying out the intrinsic protection may be impaired.
The unit must be placed on a level, non-flammable surface away from flammable
materials.
Use appropriate vessels / tubes for temperature required. Ensure that the
operating temperature is less than the maximum operating temperature of your
sample material.
Clean the unit only with a damp cloth. Do not use chemical cleaning agents.
Before using any cleaning or decontamination method except those
recommended in this manual, users should check with the Biometra Service
Department that the proposed method will not damage the equipment.
Do not make modifications to the design of the unit.
The ThermoShaker TSC has to be used only with a power supply compatible with
the connection port and with similar electrical parameters like the included power
supply. It is highly recommended only to use this supplied power supply.

Manual Biometra TSC ThermoShaker, Vers. 01_2019
3
Electrical Safety:
Connect only to a power supply with a voltage corresponding to that on the serial
number label at the rear of the unit.
The TSC Thermoshaker has to be used only with a power supply compatible with the
connection port and with similar electrical parameters like the included power supply.
It is highly recommended only to use this supplied power supply.
Ensure that the mains switch and isolating device (external power supply) are easily
accessible during use.
Do not plug the unit into the mains outlet without grounding, and do not use extension
lead without grounding.
Before moving, disconnect at the power supply socket.
To turn off the unit completely, disconnect the external power supply from the mains
outlet.
Never fill liquid directly into the blocks (always use vessels).
If liquid is spilt inside the unit, disconnect it from the power supply and have it
checked by a competent person.
Disconnect the mains before removing the outer cover. Note there are no user
serviceable parts inside in the unit. (Warranty is void if cover has been removed by
user!)
During Operation:
Do not leave the operating unit unattended.
Do not impede the platform motion during operation.
Do not operate the unit in environments with aggressive or explosive chemical
mixtures.
Do not operate the unit if it is faulty or been incorrectly installed.
For indoor use only.
Do not operate the unit outside the laboratory premises.
Do not check the temperature by touch. Use a thermometer.
Do not touch surfaces which become hot during high temperature operation.
Do not put any hot blocks on inflammable surfaces.
To reduce the risk of eye injury during high temperature operation, use safety goggles
or spectacles.
Biological & Cchemical Safety:
It is the user's responsibility to carry out appropriate decontamination if hazardous
material is spilt on or inside the equipment.

Manual Biometra TSC ThermoShaker, Vers. 01_2019
4
3 Scope of Delivery
The Biometra TSC ThermoShaker (Order No. 846-051-600/690) is delivered with
Fig. 1: Delivered parts
1 x ThermoShaker apparatus (Fig. 1/1)
1 x External power supply unit + cable (Fig. 1/2)
2 x Spare rubber belt (Fig. 1/3)
4 x Rubber spacers for block screws
1 x Manual
Interchangeable block modules (Fig. 2) have to be ordered separately and will
be delivered separately.
1
2
3

Manual Biometra TSC ThermoShaker, Vers. 01_2019
5
4 Accessories
Interchangeable block-modules
Order No. Description
846-051-615 Interchangeable block module for TSC, 24 x 1.5 ml tubes
846-051-616 Interchangeable block module for TSC, 24 x 2.0 ml tubes
846-051-612 Interchangeable block module for TSC, 20 x 0.2 ml + 12 x 1.5 ml tubes
846-051-613 Interchangeable block module for TSC, 20 x 0.5 ml + 12 x 1.5 ml tubes
846-051-614 Interchangeable block module for 96 well microtiter plates or 96 x 0.2 ml tubes





846-051-615 24 x 1.5 ml tubes
846-051-616 24 x 2.0 ml tubes
846-051-612 20 x 0.2 ml + 12 x 1.5 ml tubes
846-051-613 20 x 0.5 ml + 12 x 1.5 ml tubes
846-051-614 96 well microtiter plates or 96 x 0.2 ml tubes
Fig. 2: Biometra TSC ThermoShaker and interchangeable block modules

Manual Biometra TSC ThermoShaker, Vers. 01_2019
6
5 General Information
The TSC ThermoShaker is
a compact bench top
shaking incubator, ideal for
all applications requiring
heating, cooling and shaking
in microtubes up to 2.0 ml,
within the temperature range
of -15 °C below room
temperature (RT) to +100 °C.
The intensive mixing
operation and the
incubation/heating/cooling
mode can be used either
combined or independently
from each other, i.e. the
device can work as a
thermoshaker, incubator
without shaking/mixing or as
shaker/mixer without temperature control.
The TSC ThermoShaker is applicable for DNA and RNA analysis, extraction of lipids and
other cell components, DNA library creation, biochemical studies of enzymatic reactions and
processes, extraction of metabolites from cellular material, preparation of samples for
electrophoresis, etc.
The TSC ThermoShaker provides:
Peltier elements for active cooling
Variable speed, variable temperature micro tube thermoshaker
Gentle to vigorous mixing of samples (2 mm shaking orbit)
Soft start function
Even amplitude throughout the shaker platform
Timed shaking operation (1 min. to 96 hours) with buzzer and automatic
switch-off
Set parameters will be saved
Low voltage power supply (for safe cold room operation)

Manual Biometra TSC ThermoShaker, Vers. 01_2019
7
6 Installation
6.1 Unpack and Check
Unpack and carefully examine the TSC ThermoShaker. Report any damage to Analytik
Jena. Save all packing material if damage is found.
Attention! Automatic balancing system in this product produces light metal-like
noise when moving the unit which is likely to be heard during unpacking. It is
normal occurrence and does not indicate to a fault!
Do not attempt to operate this device if physical damage is present.
If you would like to send the unit back to us, please read the return instructions (page 17).
6.2 Installation
Place the apparatus upon even horizontal non-flammable surface away from any flammable
material.
To provide optimum ventilation ensure clearance around the apparatus: 20 cm on each side.
Ensure additional clearance from the bottom side and do not place any object below the unit.
Plug the external power supply unit (AC/DC adapter supplied with the shaker) into the 12 V
socket at the rear side of the apparatus.
6.3 Installation of Block Modules
Attention: Installation and change of block modules have to be performed
only when the Power switch is turned off and the external power supply is
disconnected from the mains outlet.
Choose the block module.
Connect the plug to the contact terminal according to Fig. 3/1 on the bottom side of the block
module. Make sure that the connector is mounted tightly.
Fig. 3: Connecting block modules
Align the block module that the warning labels are facing the front of the unit.
Secure with the four knurled screws.
Installing the 96-well block module, drive one by one 4 screws for several turns and fix them
with the hexagonal key (included with the block module.
1

Manual Biometra TSC ThermoShaker, Vers. 01_2019
8
6.4 Changing Block Modules
Turn the power switch to off and disconnect the external power supply from the mains outlet.
Remove the four knurled screws (Fig. 4/1) and disconnect the 10 way plug (Fig. 4/2).
Fig. 4: Changing block modules
Select the new block module.
Install the block module according to 6.3.
Attention:
Please handle the block modules carefully, do not let them drop.
Please disconnect and connect the 10 way plug carefully, do not damage it.
10 way plug

Manual Biometra TSC ThermoShaker, Vers. 01_2019
9
7 Operation of TSC ThermoShaker
Before starting, please
check the tubes / microtiter plates before using.
be sure that tubes / microtiter plates are thermo-resistant.
don't heat the tubes / microtiter plates over the melting point of the material they are
made of (use thermo-resisting polypropylene tubes).
remember that thin-walls tubes have a higher thermo-conducting factor.
Under the action of high temperature (> 85°C) tube caps can open, thus causing sample
volume shrinkage or potential health risk when working with infected material. To prevent
such cases it is recommended to use tubes with cap lock of Safe-Lock®type.
For efficient mixing it is recommended to fill test tubes up to 75% of the rated volume.
Starting Operation:
Connect the power supply unit to the mains. Switch on by using the on-off switch at the rear
side of the TSC (Fig. 5).
Fig. 5: Rear side of the TSC
The upper line of the display (settings) shows time, RPM and temperature set earlier. (Fig. 6)
The lower line of the display (actuals) shows current readings of the same parameters
(STOP - time, 000 - RPM, thermoblock temperature °C, which automatically starts rising
according to the temperature set in the upper line). (Fig. 6)
Fig. 6: Control panel
1
2
3
4
5
On/off switch